簡要描述:Thermo A36742 POROS CaptureSelect貨號: A36742POROS CaptureSelect AAVX Affinity Resin is engineered to addres
詳細介紹
品牌 | Thermofisher Scientific/賽默飛世爾 | 貨號 | A36742 |
---|---|---|---|
規(guī)格 | 盒 | 供貨周期 | 一周 |
主要用途 | 科研單位實驗用 | 應用領域 | 醫(yī)療衛(wèi)生,食品,化工,生物產(chǎn)業(yè),制藥 |
Thermo A36742 POROS CaptureSelect
Thermo A36742 POROS CaptureSelect
Thermo Scientific™
POROS™ CaptureSelect™ AAVX Affinity Resin
貨號: A36742
POROS CaptureSelect AAVX Affinity Resin is engineered to address the high selectivity and capacity requirements for large-scale downstream purification of a broad range of naturally occurring and synthetic adeno-associated virus (AAV) serotypes used for gene therapy applications. POROS CaptureSelect AAVX resin has demonstrated binding reactivity towards a set of AAV serotypes that includes AAV1 to AAV8, and AAVrh10 as well as synthetic serotypes.
Thermo A36742 POROS™ CaptureSelect™ AAVX Affinity Resin
Features of POROS CaptureSelect AAVX resin include:
• One-step AAV purification from crude material with high purity and yield
• High specificity and capacity, maximizing yield by significantly reducing process steps
• Superior capacity maintained at high flow rates
• Excellent scalability and easier handling and packing due to rigid polymeric bead
• Non-animal derived
POROS CaptureSelect AAVX Affinity Resin enables a robust, fast, and platformable purification process for wide-ranging AAV serotypes with excellent purity and yield obtained in one step. This resin comes with complete technical and regulatory support.
View other viral vector resins and supporting products ?
Main characteristics
Matrix: cross-linked poly(styrene-divinylbenzene) POROS beads
Average particle size: 50 µm
Ligand: CaptureSelect AAVX affinity ligand
Binding capacity: >1x1013 genome copies/mL of resin
Elution conditions: acidic elution with 0.1 M glycine, pH 3.0
Mechanical resistance: 100 bar (1,450 psi; 10 MPa)
Formulation buffer: 18% (v/v) ethanol
Free of animal components
CaptureSelect products contain affinity ligands based on recombinant single-domain antibody fragments (VHH) created by a proprietary technology. The VHH affinity ligand is a 12 to 15 kDa fragment comprising the three complementarity-determining regions (CDRs) that form the antigen-binding domain, efficiently produced in the yeast Saccharomyces cerevisiae by a production process free of any animal components (Animal Origin-Free).
貨號 單位規(guī)格
A36742 250 mL
A36739 10 mL
A36740 25 mL
A36741 50 mL
A36743 1,000 mL
A36744 5,000 mL
A36745 10,000 mL
規(guī)格
配基類型:CaptureSelect AAVX affinity ligand
粒徑:50 μm
數(shù)量:250 mL
產(chǎn)品線:POROS™
結合功能:>1x1013 genome copies/mL of resin
運輸條件:Wet Ice
基質(zhì):Cross-linked poly(styrene-divinylbenzene) POROS beads
色譜柱類型:Affinity
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